In the vertebrates, histocompatibility is ultimately an artifact of medical intervention, considering that vertebrates are only naturally challenged to immunologically tolerate individuals of their own species during pregnancy. If the colonies are compatible they will often blend together, and depending on the species will form a single chimeric individual or they will reject, during which the interacting tissues are destroyed. These types of animals, specifically the sponges, hydroids, anemones, bryozoans and ascidians, are permanently attached to the substratum and typically propagate continuously via asexual reproduction, which often results in physical contact between adjacent colonies. Although this phenomenon is pervasive throughout the animal kingdom, we often find examples of highly polymorphic, naturally occurring allorecognition systems within the colonial marine invertebrates. Book excerpt: The ability to molecularly distinguish self from non-self is a common feature throughout the metazoa and is the fundamental basis of immune function. This book was released on 22 September 2021 with total page null pages. Download or read book entitled Isolation and Characterization of Uncle Fester, an Allorecognition Molecule in the Primitive Chordate, Botryllus Schlosseri written by and published by Stanford University online.
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